Bas van Breukelen – Bioinformatic tools for Proteomics

Bas van Breukelen – Bioinformatic tools for Proteomics

  • Padualaan 8
  • 3584CH Utrecht, Netherlands
  • +31(0)302539761


Bas van Breukelen focuses on the analysis of data originating from proteomic experiments. Bioinformatics tools are developed to identify and quantify proteins presents in those very large datasets. In addition software and algorithms are developed that aid statistical analysis and data visualization.

Highlighted publications

See my citations on Google Scholar
  • Smit MA1, Maddalo G2, Greig K1, Raaijmakers LM3, Possik PA1, van Breukelen B3, Cappadona S3, Heck AJ3, Altelaar AF4, Peeper DS5. ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma. Mol Syst Biol. 2014 Dec 23;10:772. PMID: 25538140. [PubMed] [Read by QxMD]
  • Binai NA1, Bisschops MM, van Breukelen B, Mohammed S, Loeff L, Pronk JT, Heck AJ, Daran-Lapujade P, Slijper M. Proteome adaptation of Saccharomyces cerevisiae to severe calorie restriction in Retentostat cultures. J Proteome Res. 2014 Aug 1;13(8):3542-53. PMID: 25000127. [PubMed] [Read by QxMD]
  • Liu F1, van Breukelen B1, Heck AJ2. Facilitating protein disulfide mapping by a combination of pepsin digestion, electron transfer higher energy dissociation (EThcD), and a dedicated search algorithm SlinkS. Mol Cell Proteomics. 2014 Oct;13(10):2776-86. PMID: 24980484. [PubMed] [Read by QxMD]
  • Walzer M1, Pernas LE2, Nasso S3, Bittremieux W4, Nahnsen S1, Kelchtermans P5, Pichler P6, van den Toorn HW7, Staes A8, Vandenbussche J8, Mazanek M6, Taus T6, Scheltema RA9, Kelstrup CD10, Gatto L11, van Breukelen B7, Aiche S12, Valkenborg D13, Laukens K4, Lilley KS14, Olsen JV10, Heck AJ7, Mechtler K6, Aebersold R15, Gevaert K8, Vizcaíno JA16, Hermjakob H16, Kohlbacher O1, Martens L17. qcML: an exchange format for quality control metrics from mass spectrometry experiments. Mol Cell Proteomics. 2014 Aug;13(8):1905-13. PMID: 24760958. [PubMed] [Read by QxMD]
  • Guerreiro AC1, Benevento M1, Lehmann R2, van Breukelen B1, Post H1, Giansanti P1, Maarten Altelaar AF3, Axmann IM4, Heck AJ3. Daily rhythms in the cyanobacterium synechococcus elongatus probed by high-resolution mass spectrometry-based proteomics reveals a small defined set of cyclic proteins. Mol Cell Proteomics. 2014 Aug;13(8):2042-55. PMID: 24677030. [PubMed] [Read by QxMD]

 People working on Bioinformatics

[profilelist pi=”bas-van-breukelen” orderby=”last_name”]


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