Advanced Biomolecular Mass Spectrometry and Proteomics course 2022 Topics: Ionization techniques and MS platforms Ion mobility Peptide separation techniques and (alternative)Fragementation Methods Quantitative proteomics Phosphoproteomics Proteomics @ Sanquin (plasma proteomics) Top down proteomics and cross-linking MS Native MS Metabolomics Targeted Proteomics (SRM, DIA, DDA) Glycoproteomics REGISTER HERE...
At the interface of art and science - athletic dancing bodies depict the equally flexible antibodies present in our bodies! Inspired by the research of the Hecklab of Utrecht University, the researchers collaborated with video performers from Sensu and the dancers from the Aerialettes, to visualize...
To further explore the boundaries of single particle native mass spectrometry using charge detection on an Orbitrap Tobias Wörner Utrecht University tracked the flight paths of individual virus particles for several kilometers and observed that their trajectories are remarkably stable. This in-depth analysis of the...
Er is een eiwitrevolutie aan de gang. De ene na de andere belangrijke ontwikkeling wordt gemeld. AlphaFold, een AI-programma ontwikkeld door Googles onderzoeksafdeling DeepMind, presenteerde onlangs baanbrekend onderzoek. Hoogleraar Albert Heck: ‘Het is zeker een paradigmawisseling, maar magie is het niet.’ https://www.vprogids.nl/2021/44/editie?pagina=24...
BILLERICA, Massachusetts – August 8, 2020 – Bruker Corporation (Nasdaq: BRKR) today announced a collaboration with Utrecht University to advance the study of the 3-D structures and interactions of proteins by mass spectrometry. The laboratory of Albert Heck at Utrecht University has been a leader...
We demonstrate single-particle charge detection mass spectrometry on an Orbitrap for the analysis of megadalton biomolecular assemblies. We establish that the signal amplitudes of individual ions scale linearly with their charge, which can be used to resolve mixed ion populations, determine charge states and thus...
How paired PSII–LHCII supercomplexes mediate the stacking of plant thylakoid membranes unveiled by structural mass-spectrometry Utrecht scientists uncover the molecular machinery in the chloroplasts of plants. This opens the way for research into protein interactions in protein complexes on the cell surface. They publish their findings...
The Barford group at @MRC_LMB revealed the structure of the kinetochore CCAN complex assembled onto a centromeric nucleosome, using our Domenico Fasci’s @UUBeta cross-linking MS data to validate assignments in the EM maps. #EPICXS #proteomics @xlinkx_pd https://nature.com/articles/s41586-019-1609-1...