We demonstrate single-particle charge detection mass spectrometry on an Orbitrap for the analysis of megadalton biomolecular assemblies. We establish that the signal amplitudes of individual ions scale linearly with their charge, which can be used to resolve mixed ion populations, determine charge states and thus...
How paired PSII–LHCII supercomplexes mediate the stacking of plant thylakoid membranes unveiled by structural mass-spectrometry Utrecht scientists uncover the molecular machinery in the chloroplasts of plants. This opens the way for research into protein interactions in protein complexes on the cell surface. They publish their findings...
The Barford group at @MRC_LMB revealed the structure of the kinetochore CCAN complex assembled onto a centromeric nucleosome, using our Domenico Fasci’s @UUBeta cross-linking MS data to validate assignments in the EM maps. #EPICXS #proteomics @xlinkx_pd https://nature.com/articles/s41586-019-1609-1...
On March 1st, 2017 we had our festive kickoff of our three new Mass Spectrometers. [gallery columns="4" link="file" ids="3167,3168,3169,3170,3171,3172,3173,3175,3176,3177,3178,3179,3183,3184,3185,3186,3187,3188,3189,3190,3191,3192"] More information (in Dutch) can be found here ...
Professor Albert Heck has received an honory membership of the Spanish Proteomics Society. Heck was honored during the Opening Ceremony of the 6th Congress of the Spanish Proteomics Society in Cadiz on November 15th 2016. On the picture Heck receives the award from Angel García, President of the...
Researchers at Utrecht University, including Albert Heck and Simone Lemeer, have revealed structural changes in a receptor that plays a key role in many types of cancer. The changes occur before and during receptor activation. These findings provide novel clues to develop medication to target...
The Netherlands Society for Biochemistry and Molecular Biology (NVBMB) each year acknowledges the work of a highly talented young Dutch biochemist or molecular biologist with at least two years of postdoctoral experience. Important criteria include scientific quality, publication in top journals, productivity, creativity, international experience...
The Royal Netherlands Academy of Arts and Sciences has awarded the 2016 Dr H.P. Heineken Prize for Biochemistry and Biophysics (a sum of USD 200,000) to Jennifer Doudna, Professor of Biomedical Sciences at the University of California in Berkeley (United States). Jennifer Doudna will receive the...