Author: Bas van Breukelen

Richard Scheltema group works on unraveling protein complex topology and dynamics by mass spectrometry. Research focuses on the development of advanced LC/MS-MS platforms and analysis software to provide an in-depth, quantitative view on and spatial information between the proteins & small molecules under investigation. Highlighted publications See my...

Utrecht University has appointed Dr. Alexander Makarov as Professor of High Resolution Mass Spectrometry at the Department of Chemistry and the Bijvoet Center. Makarov is Director of Global Research for Life Sciences Mass Spectrometry at Thermo Fisher Scientific. His appointment is a further strengthening of the close research collaboration...

ABSTRACT: Post-translational modifications (PTMs) play an impor-
tant role in the regulation of protein function. Mass spectrometry based
proteomics experiments nowadays identify tens of thousands of PTMs in
a single experiment. A wealth of data has therefore become publically
available. Evidently the biological function of each PTM is the...

Next-generation proteomics: towards an integrative view of proteome dynamics The proteome is extremely multifaceted due to splicing and protein modifications, further amplified by the interconnectivity of proteins into complexes and signaling networks that are highly divergent in time and space. Proteome analysis heavily relies on mass...